Current Clinical Trials for OLT1177® Dapansutrile
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Completed Clinical Trials
(click on study title to link to clinicaltrials.gov or clinicaltrialsregister.eu)
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Study OLT1177-01 | OLT1177® Gel Safety Study
A Phase 1 randomized, placebo-controlled, sequential ascending-dose safety and pharmacokinetic study of healthy volunteers after administration of single or multiple dose(s) of investigational drug (OLT1177® Gel or Placebo Gel). A total of 36 subjects were enrolled across 6 cohorts randomized in a ratio of 5 active to 1 placebo. Study OLT1177-02 | OLT1177® Gel for Knee OA A Phase 2a randomized, placebo-controlled safety and efficacy study of subjects with moderate-to-severe osteoarthritis of the knee following treatment with investigational drug (OLT1177® Gel or Placebo Gel) for two weeks. A total of 79 subjects were enrolled and randomized in a ratio of 2 active to 1 placebo. Study OLT1177-03 | OLT1177® Gel for Knee OA A Phase 2b randomized, placebo-controlled safety and efficacy study of subjects with moderate-to-severe osteoarthritis of the knee following treatment with investigational drug (OLT1177® Gel or Placebo Gel) for six weeks. A total of 202 subjects were enrolled and randomized in a ratio of 1 active to 1 placebo. Study OLT1177-04 | OLT1177® Capsules Safety Study A Phase 1 randomized, placebo-controlled, sequential ascending-dose safety and pharmacokinetic study of healthy volunteers after administration of single or multiple dose(s) of investigational drug (OLT1177® Capsules or Placebo Capsules). A total of 35 subjects were enrolled across 6 cohorts randomized in a ratio of 5 active to 1 placebo. Study OLT1177-05 | OLT1177® Capsules for an Acute Gout Flare
A Phase 2a, single-center, sequential, adaptive dose progression proof-of-concept safety and efficacy study of orally administered investigational drug (OLT1177® Capsules) in subjects with an acute gout flare. |